evaluation-impact-new-cooling-cell-processor-system-on-islet-cell

Evaluation of the Impact of a New Cooling Cell Processor System on Islet Cell Isolation Facility

Standard cell therapy equipment, including the gold standard cell processor to purify human islets for clinical transplantation, is rarely refrigerated, ...

Hamad Medical Corporation

Institute Pasteur Lille

Univ-Lille, Inserm, CHU Lille, Institute Pasteur Lille, U1190 - EGID F-59000 Lille

Hematopoietic stem cell transplantation (HSCT) offers potentially curative therapy for many hematologic and nonhematologic conditions. As a successful outcome of Qatar's National Cancer Strategy, the HSCT program was started in the National Center for Cancer Care and Research (NCCCR) in October 2015. The HSCT program in NCCCR is the only transplant program in Qatar and self-sufficient with all three core components: the stem cell collection facility, the stem cell processing facility, and the clinical program, which are locally available at Hamad Medical Corporation. In this paper, we report on the outcomes of the first 16 patients who underwent autologous stem cell transplantations (ASCTs) in our center. A total of 17 ASCT have been performed for 16 adult (≥14years) patients. Thirteen of the 16 patients were eligible for disease evaluation at Day 100 post-ASCT. Among these patients, the overall response rate on Day 100 was 92% (complete remission, 61%; very good partial remission/partial remission, 31%) and stable disease occurred in 6%. The procedure was very well tolerated by all patients. At the time of writing this report, all patients are alive; however, one patient (6%) had disease relapse. The Day 100 post-ASCT nonrelapse mortality rate was 0%. Launching the HSCT program represents a historic milestone in the development of the health-care sector in Qatar. The 1st year of this program was very fruitful with the accomplishment of 17 successful transplants. We are in the process of starting the allogenic HSCT early next year. This would represent the next significant milestone for cancer care in Qatar.

Naziha Menasria

Qatar Metabolic Institute

Hamad Medical Corporation

Evaluation of the Impact of a New Cooling Cell Processor System on Islet Cell Isolation Facility

Naziha Menasria

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Hamad Medical Corporation

Evaluation of the Impact of a New Cooling Cell Processor System on Islet Cell Isolation Facility

Qatar Metabolic Institute