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Production of Large Numbers of Size-controlled Tumor Spheroids Using Microwell Plates

Tumor spheroids are increasingly recognized as an important in vitro model for the behavior of tumor cells in three dimensions. More physiologically ...

University of Calgary

The authors report their experience of the secondary treatment of forearm defects secondary to gunshot injuries. The lesions encountered involved both soft tissues and bone. After using classical techniques consisting of fibula or iliac crest osteocutaneous free flaps, they used, whenever possible, a second metatarsal osteocutaneous free flap, which enabled them to conduct a comparative study of these different procedures and they concluded on the superiority of this latter type of flap. Their experience is based on 28 cases, including 16 cases of second metatarsal osteocutaneous free flap.

[Value of a free osteocutaneous flap from the second metatarsal bone in the management of substance loss in the forearm, caused by gunshot wounds. Apropos of an experience in 28 cases].

The authors report a series of 27 war injuries to the femoral nerve which represent approximately 1% of all of the war injuries to peripheral nerves operated in our department since the Islamic revolution in Iran in 1978 and during the 8 years of the war between Iran and Iraq. All of the victims presented with associated lesions: abdominal (24 laparotomies, including 10 colostomies) and/or vascular (3 iliac artery by-pass grafts). We divided the cases into 3 groups. In Group 1 (18 cases), the femoral nerve had a mean defect of 8 centimetres which was grafted. In Group 2 (4 cases), the nerve was simply compressed by fibrosis and/or metallic bodies and was released. In Group 3 (5 cases), the nerve trunk had a partial loss of substance which was grafted. The motor results were very satisfactory (M3 to M5) in the 3 groups with muscular recovery in about 2 years.

[War injuries of the femoral nerve. Apropos of a series of 27 cases].

In gait analysis, there is growing awareness of the need to simultaneously measure shear and vertical forces for the diagnosis and treatment assessment of pathological foot disorders. This is especially the case in the measurement of the forces between the plantar surface of the foot and the shoe. Although clinical awareness of the need to simultaneously measure shear and vertical forces under the foot has increased little has been done to provide the technology. This is mainly due to the difficulty in constructing devices capable of carrying out this task in the in-shoe environment. The aim of this paper is to describe the development and characteristics of a miniature triaxial transducer measuring 10 x 10 x 2.7 mm and a weight of only 2 g. This transducer is capable of simultaneously measuring three orthogonal forces under any location of the plantar surface of the foot utilizing a single element piezoelectric copolymer P(VDF-TrFE). Transducer sensitivity, linearity, hysteresis, cross-talk and temperature dependence is presented. As well as in-shoe force measurement, this triaxial transducer could have other biomedical and general engineering applications, e.g., prosthetic interface forces, handgrip forces, sport, robotics, etc.

Design, development, and characteristics of an in-shoe triaxial pressure measurement transducer utilizing a single element of piezoelectric copolymer film.

The aim of this study was to verify the role of Vitamins C and E on the cognitive function of young and aged mice. First and second groups of young animals (aged 3 months) received either Vitamin E (250mg/kg per day) or Vitamin C (300mg/kg per day) for 60 days. Third group was treated with the combination of Vitamin E (250mg/kg per day) and Vitamin C (300mg/kg per day) for 60 days. The control group received only vehicle. The aged animal group (aged 15 months) were treated as the young group. Passive avoidance method was used for the assessment of cognitive function in both young and aged animals. The results indicated a significant improvement in the cognitive function of aged mice while there were no significant changes in young animals.

Golsa Razian

Department of Comparative Biology & Experimental Medicine,
Faculty of Veterinary Medicine,
Department of Comparative Biology & Experimental Medicine, Faculty of Veterinary Medicine

University of Calgary

Production of Large Numbers of Size-controlled Tumor Spheroids Using Microwell Plates

Golsa Razian

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Comparative Biology & Experimental Medicine,Faculty of Veterinary Medicine,Department of Comparative Biology & Experimental Medicine, Faculty of Veterinary Medicine

University of Calgary

Production of Large Numbers of Size-controlled Tumor Spheroids Using Microwell Plates

Department of Comparative Biology & Experimental Medicine,
Faculty of Veterinary Medicine,
Department of Comparative Biology & Experimental Medicine, Faculty of Veterinary Medicine