Mark Ungrin

Department of Comparative Biology & Experimental Medicine,
Faculty of Veterinary Medicine,
Department of Comparative Biology and Experimental Medicine,
Comparative Biology and Experimental Medicine,
Biomedical Engineering Graduate Program,
Department of Comparative Biology & Experimental Medicine, Faculty of Veterinary Medicine

University of Calgary

BIOGRAPHY

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PUBLICATIONS

Strict control of telomerase activation using Cre-mediated inversion.

BMC biotechnology , 2006 | Pubmed ID: 16504006

Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates.

PloS one , 2008 | Pubmed ID: 18270562

The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis.

Human molecular genetics Dec, 2002 | Pubmed ID: 12444098

Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.

Proceedings of the National Academy of Sciences of the United States of America Mar, 2002 | Pubmed ID: 11904422

Soft lithography: masters on demand.

Lab on a chip Aug, 2008 | Pubmed ID: 18651082

Phenotypic analysis of human embryonic stem cells.

Current protocols in stem cell biology Aug, 2007 | Pubmed ID: 18785161

An automated system for delivery of an unstable transcription factor to hematopoietic stem cell cultures.

Biotechnology and bioengineering Jun, 2009 | Pubmed ID: 19266473

Micropatterning of human embryonic stem cells dissects the mesoderm and endoderm lineages.

Stem cell research Mar, 2009 | Pubmed ID: 19383420

Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation.

Biomaterials Jan, 2011 | Pubmed ID: 20864164

Geometric control of cardiomyogenic induction in human pluripotent stem cells.

Tissue engineering. Part A Aug, 2011 | Pubmed ID: 21417693

Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics.

Biotechnology and bioengineering Apr, 2012 | Pubmed ID: 22139975

Scalable cardiac differentiation of human pluripotent stem cells as microwell-generated, size controlled three-dimensional aggregates.

Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 25070323

Human islet function following 20 years of cryogenic biobanking.

Diabetologia Jul, 2015 | Pubmed ID: 25930156

The microwell-mesh: A novel device and protocol for the high throughput manufacturing of cartilage microtissues.

Biomaterials Sep, 2015 | Pubmed ID: 26010218

A Simple and Low-Cost Monitoring System to Investigate Environmental Conditions in a Biological Research Laboratory.

PloS one , 2016 | Pubmed ID: 26771659

Climbing the mountain: experimental design for the efficient optimization of stem cell bioprocessing.

Journal of biological engineering , 2017 | Pubmed ID: 29213303

Bioengineered human pseudoislets form efficiently from donated tissue, compare favourably with native islets in vitro and restore normoglycaemia in mice.

Diabetologia 09, 2018 | Pubmed ID: 29971529

Bioprocessing of Mesenchymal Stem Cells and Their Derivatives: Toward Cell-Free Therapeutics.

Stem cells international , 2018 | Pubmed ID: 30275839

Oxygenation in cell culture: Critical parameters for reproducibility are routinely not reported.

PloS one , 2018 | Pubmed ID: 30325922

Formation of organotypic testicular organoids in microwell culture†.

Biology of reproduction Jun, 2019 | Pubmed ID: 30927418

Stirred Suspension Bioreactor Culture of Porcine Induced Pluripotent Stem Cells.

Stem cells and development Sep, 2019 | Pubmed ID: 31264514

INSTITUTIONS

University of Calgary

University of Alberta

JOVE ARTICLES

Production of Large Numbers of Size-controlled Tumor Spheroids Using Microwell Plates

Golsa Razian¹,

Yang Yu¹,

Mark Ungrin¹

¹Department of Comparative Biology & Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary

Bioengineering

Aggregate Size Optimization in Microwells for Suspension-based Cardiac Differentiation of Human Pluripotent Stem Cells

Celine L. Bauwens^*,1,

Derek Toms^*,2,

Mark Ungrin²

¹Institute of Biomaterials and Biomedical Engineering, University of Toronto,

²Department of Comparative Biology and Experimental Medicine, University of Calgary

Developmental Biology

Generation of Porcine Testicular Organoids with Testis Specific Architecture using Microwell Culture

Sadman Sakib¹,

Yang Yu^3,4,

Anna Voigt²,

Mark Ungrin^2,3,4,

Ina Dobrinski^1,2

¹Biochemistry and Molecular Biology, University of Calgary,

²Comparative Biology and Experimental Medicine, University of Calgary,

³Biomedical Engineering Graduate Program, University of Calgary,

⁴Alberta Diabetes Institute, University of Alberta

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