Widener University

3 ARTICLES PUBLISHED IN JoVE

Bioengineering

Methods for In Vivo Biomechanical Testing on Brachial Plexus in Neonatal Piglets

Anita Singh¹, Rachel Magee¹, Sriram Balasubramanian²

¹Department of Biomedical Engineering, Widener University, ²School of Biomedical Engineering, Science and Health Systems, Drexel University

Presented here are methods to perform in vivo biomechanical testing on brachial plexus in a neonatal piglet model.

Bioengineering

A Reliable Porcine Fascio-Cutaneous Flap Model for Vascularized Composite Allografts Bioengineering Studies

Victor Pozzo^1,2,4, Golda Romano^1,2,4, Marion Goutard^1,2,4, Elise Lupon^1,2,4, Pierre Tawa^1,2,4, Aylin Acun^3,4,5, Alec R. Andrews², Corentin B. Taveau^1,2,4,6, Basak E. Uygun^1,2,3,4, Mark A. Randolph^1,2,4, Curtis L. Cetrulo^1,2,4, Alexandre G. Lellouch^1,2,4,6

¹Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, ²Vascularized Composite Allotransplantation Laboratory, Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, ³Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, ⁴Shriners Hospital for Children, ⁵Department of Biomedical Engineering, Widener University, ⁶Service de Chirurgie Plastique, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris (APHP), Université Paris Descartes

The present protocol describes the porcine fascio-cutaneous flap model and its potential use in vascularized composite tissue research.

Bioengineering

Investigating Stress-relaxation and Failure Responses in the Trachea

Anita Singh¹, Tanmay Majmudar^2,3, Adi Iyer⁴, Diya Iyer⁴, Sriram Balasubramanian³

¹Department of Biomedical Engineering, Widener University, ²Drexel University College of Medicine, ³School of Biomedical Engineering, Science and Health Systems, Drexel University, ⁴Rosetree Media School District

The present protocol determines the tensile stress-relaxation and failure properties of porcine tracheae. Results from such methods can help improve the understanding of the viscoelastic and failure thresholds of the trachea and help advance the capabilities of computational models of the pulmonary system.