National Institute for Biological Standards and Control

1 ARTICLES PUBLISHED IN JoVE

Medicine

Reproducibility and Harmonization in Research Using Biological Standards: The Example of Platelet Agonist Collagen-Related Peptide

Carmen H. Coxon¹, Peter Rigsby¹

¹Medicines and Healthcare products Regulatory Agency

Here we present a method to standardize the platelet agonist collagen-related peptide cross-linked (CRP-XL) using light transmission aggregometry. While the protocol is targeted at platelet function, the experimental process can be applied to most biological molecules and bioassays to ensure scientific rigor and reproducibility.