JoVE Logo
Faculty Resource Center

Sign In

China Resources Sanjiu Modern Chinese Medicine Pharmaceutical Co., Ltd

1 ARTICLES PUBLISHED IN JoVE

image

Chemistry

An Improved Technique for Trimethylamine Detection in Animal-Derived Medicine by Headspace Gas Chromatography-Tandem Quadrupole Mass Spectrometry
Hui Ye 1, Xuemei Liu 1, JiaBao Liao 2, Haozhou Huang 3, Lin Huang 1, Yang Bao 1, Hongyan Ma 1, Junzhi Lin 4, Xiaoming Bao 5, Dingkun Zhang 1, Runchun Xu 1
1State Key Laboratory of Southwestern Chinese Medicine Resources, Pharmacy School, Chengdu University of Traditional Chinese Medicine, 2China Resources Sanjiu Modern Chinese Medicine Pharmaceutical Co., Ltd, 3Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, 4TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, 5Shimadzu (China) Co., Ltd

Here, a headspace gas chromatography-tandem quadrupole mass spectrometry (HS-GC-MS/MS) method suitable for the determination of trimethylamine (TMA) in animal-derived medicines is described. The protocol includes sample pretreatment, headspace treatment, analysis conditions, methodological validation, and the determination of TMA in animal-derived medicines.

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved