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Meiji University

2 ARTICLES PUBLISHED IN JoVE

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Behavior

fMRI Validation of fNIRS Measurements During a Naturalistic Task
J. Adam Noah 1, Yumie Ono 2, Yasunori Nomoto 2, Sotaro Shimada 2, Atsumichi Tachibana 3, Xian Zhang 1, Shaw Bronner 1, Joy Hirsch 1,5
1Department of Psychiatry, Yale School of Medicine, 2Department of Electronics and Bioinformatics, Meiji University, 3Department of Histology and Neurobiology, Dokkyo Medical University School of Medicine, 4ADAM Center, Department of Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, 5Department of Neurobiology, Yale School of Medicine

We present a method to compare functional brain activity recorded during a naturalistic task using fNIRS with activity recorded during fMRI.

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Behavior

Testing Animal Anxiety in Rats: Effects of Open Arm Ledges and Closed Arm Wall Transparency in Elevated Plus Maze Test
Yasuyuki Horii 1, Iain McTaggart 2, Maiko Kawaguchi 1
1Laboratory of Animal Behavior and Environmental Science, School of Agriculture, Meiji University, 2Laboratory of Agri-environmental Science, School of Agriculture, Meiji University

Rats' anxiety-like behavior tested by the elevated plus maze varies highly depending on the testing environment. Here we show how apparatus settings, especially arm structure, affect behavior on the maze, and we explain a reliable protocol to detect effects of anxiolytic drugs. This report will contribute to anxiety research.

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