Center for Neuroscience at the University of Pittsburgh

1 ARTICLES PUBLISHED IN JoVE

Neuroscience

In-Vivo Calcium Imaging of Sensory Neurons in the Rat Trigeminal Ganglion

Jeremy Y. Gedeon^1,2,3, Jorge Baruch Pineda-Farias^2,3, Michael S. Gold^2,3

¹Center for Neuroscience at the University of Pittsburgh, ²Department of Neurobiology, University of Pittsburgh School of Medicine, ³Pittsburgh Center for Pain Research, University of Pittsburgh

Genetically encoded calcium indicators (GECI) enable a robust, population-level analysis of sensory neuron signaling. Here, we have developed a novel approach that allows for in vivo GECI visualization of rat trigeminal ganglia neuron activity.