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Guangdong Second Provincial General Hospital

1 ARTICLES PUBLISHED IN JoVE

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Bioengineering

Preservation of Porcine Donation after Circulatory Death (DCD) Liver by Perfusion and Orthotopic Liver Transplantation
Qing OuYang *1, Xiaoyu Tan *1, Liyue Sun *2, Weijian Kuang *3, Xiran He 3, Mingju Liang 3, Yujian Zheng 1, Ru Ji 1, Mengchao Wang 1, Zhiping Huang 1, Jun Liu 1, Jianxiong Chen 1, Feiwen Deng 4, Huanwei Chen 4, Feng Huo 1
1Department of Hepatobiliary Surgery and Liver Transplant Center, PLA General Hospital of Southern Theatre Command: People's Liberation Army General Hospital of Southern Theatre Command, 2Second Department of Oncology, Guangdong Second Provincial General Hospital, 3Guangdong Shunde Industry Design Institute (Guangdong Shunde Innovative Design Institute), 4Department of Hepatopancreas Surgery, Foshan First People's Hospital

This protocol outlines the methodology of establishing a porcine model utilizing variable temperature-controlled Machine Perfusion (MP) for the preservation of the donor liver, followed by orthotopic liver transplantation (OLTx). It aims to promote the success rate of OLTx using donor donation after circulatory death (DCD) liver and establish a stable model.

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