Tropomodulin 3 Overexpression as a Marker for Platinum Resistance and Immune Infiltration in Ovarian CancerDingwen Xu *1, Xiaofei Hu *2, Yang Feng 1, Zhihua Lu 1, Xianmei Liu 3, Huishen Yan 1, Jianming Peng 1, Sen Luo 1, Weijuan Yao 4
1Department of Clinic, School of Medicine, Yangzhou Polytechnic College, 2Department of Nuclear Medicine, Huangshi Central Hospital, Affiliated Hospital of Hubei Institute of Technology, 3School of Biology and Engineering, Guizhou Medical University, 4Hemorheology Center, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center
Tropomodulin 3 (TMOD3) has been increasingly studied in tumors in recent years. This study is the first to report that TMOD3 is highly expressed in ovarian cancer and is closely associated with platinum resistance and immune infiltration. These results could help improve the therapeutic outcomes for ovarian cancer.
