A Multi-Electrode Array Platform for Modeling Epilepsy Using Human Pluripotent Stem Cell-Derived Brain AssembloidsTong Pan 1,2, Daniel C. Jaklic 1,2, Shivanshi Vaid 1,2, Grace Lin 1,2, Debora VanHeyningen 1,2, Louis T. Dang 1,2
1Division of Pediatric Neurology, Department of Pediatrics, Michigan Medicine, Ann Arbor, 2Michigan Neuroscience Institute, University of Michigan, Ann Arbor
This protocol aims to stably plate dorsal-ventral fused assembloids on multi-electrode arrays for modeling epilepsy in vitro.