Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229

1 ARTICLES PUBLISHED IN JoVE

Bioengineering

Comprehensive Characterization of Tissue Mineralization in an Ex Vivo Model

Constance Lesage¹, Pierre Guihard¹, Claire De Fourmestraux¹, Olivier Gauthier¹, Pierre Weiss¹, Jérome Guicheux¹, Aleksandra Mieczkowska¹, Joelle Véziers¹, Baptiste Charbonnier¹, Marie-Astrid Boutet¹, Guillaume Mabilleau^1,2

¹Nantes Université, Univ Angers, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, ²CHU Angers, Departement pathologie cellulaire et tissulaire

The proposed protocol entails a global approach to assess bone formation in the context of bone regeneration using multimodal analyses. It aims to provide qualitative and quantitative information on new bone formation, enhancing the rigor and validity of basic and pre-clinical investigations.