Sign In

University of Bradford

2 ARTICLES PUBLISHED IN JoVE

image

Biology

Laser Capture Microdissection on Surgical Tissues to Identify Aberrant Gene Expression in Impaired Wound Healing in Type 2 Diabetes
Rachael Williams *1, Irene Castellano-Pelicena *1,2, Aaiad H.A Al-Rikabi 1,3, Stephen K. Sikkink 1, Richard Baker 1, Kirsten Riches-Suman 1, M Julie Thornton 1
1Centre for Skin Sciences, University of Bradford, 2The Charles Institute of Dermatology, School of Medicine, University College Dublin, 3University of Baghdad

This technique provides a guide to inflicting ex vivo wounds, performing laser capture microdissection and quantifying changes in gene expression related to poor wound healing processes in diabetes using clinically relevant human tissue.

image

Medicine

An Experimental Approach to Induce Trips in Lower-Limb Amputees
André Luiz Felix Rodacki 1, John Gerard Buckley 2, Ana Carolina Passos de Oliveira 3, Rauce Marçal da Silva 3, Vitor Bertoli Nascimento 3
1Department of Physical Education, Federal University of Paraná, 2Department of Biomedical and Electronics Engineering, University of Bradford, 3Department of Occupational Therapy, Federal University of Paraná

An experimental approach was developed to induce trips in lower-limb amputees. The goal was to create unexpected trips and induce meaningful tripping/recovery responses. The kinematic data from one transtibial amputee confirmed that such an approach effectively elicits reactive trip recovery responses.

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved