JoVE Logo

Sign In

Hartford Hospital

1 ARTICLES PUBLISHED IN JoVE

image

Neuroscience

Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice
Lauren H. Sansing 1,2,3, Scott E. Kasner 2, Louise McCullough 1, Puneet Agarwal 2, Frank A. Welsh 4, Katalin Kariko 4
1Department of Neurology, University of Connecticut Health Center, 2Department of Neurology, School of Medicine, University of Pennsylvania, 3Department of Neurosurgery, Hartford Hospital, 4Department of Neurosurgery, School of Medicine, University of Pennsylvania

The autologous blood injection model of intracerebral hemorrhage in mice described in this protocol uses the double injection technique to minimize risk of blood reflux up the needle track, no anticoagulants in the pumping system, and eliminates all dead space and expandable tubing in the system.

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved