Induction of Cerebral Arterial Gas Embolism in RatRaoul A. Fakkert 1,2,3, Nina C. Weber 3, Benedikt Preckel 1,3, Robert A. van Hulst 1,2, Inge A. Mulder *4,5,6, Robert P. Weenink *1,2
1Department of Anesthesiology, Amsterdam UMC, 2Department of Hyperbaric Medicine, Amsterdam UMC, 3Laboratory of Experimental Intensive Care and Anesthesiology, Amsterdam UMC, 4Biomedical Engineering and Physics, Amsterdam UMC, 5Microcirculation, Amsterdam Cardiovascular Sciences, 6Neurovascular Disorders, Amsterdam Neurosciences
This protocol provides a detailed description of inducing cerebral air emboli in rats. It compares direct injection into the common carotid artery and introduction through the external carotid artery. It provides a technical description of the air bubble generator, the effect of different air volumes, and procedural challenges.
