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Guangdong Engineering Technology Research Center of Reproductive Immunology for Peri-Implantation

1 ARTICLES PUBLISHED IN JoVE

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Biology

Establishing a Mouse Model of Thin Endometrium
Mingye Chen *1,2, Junjie Tang *3, Binfa Liang 1,2, Lianghui Diao 1,2, Jie Liu 3, Qing Sun 1,2, Xian Chen 1,2
1Shenzhen Key Laboratory of Reproductive Immunology for Peri-implantation, Shenzhen Zhongshan Institute for Reproductive Medicine and Genetics, Shenzhen Zhongshan Obstetrics and Gynecology Hospital (formerly Shenzhen Zhongshan Urology Hospital), 2Guangdong Engineering Technology Research Center of Reproductive Immunology for Peri-Implantation, 3School of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University

This article describes a detailed protocol for producing a reliable and reproducible thin endometrium with a very low mortality rate and minimal intrauterine adhesions by injecting 95% ethanol into the mouse uterus within 1-3 min.

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