An Immunocompetent Murine Model for Laser Interstitial Thermal Therapy of GlioblastomaJeremy Spence 1, Santhosh S. Anandhan 1, Nimrat Kaur 1, Thatchawan Thanasupawat 1, Sabine Hombach-Klonisch *1,2, Thomas Klonisch *1,2,3,4
1Department of Human Anatomy and Cell Sciences, University of Manitoba, 2Department of Pathology, University of Manitoba, 3Department of Medical Microbiology & Infectious Diseases, University of Manitoba, 4CancerCare Manitoba
Glioblastoma is a devastating form of primary brain cancer, and laser interstitial thermal therapy is emerging as a promising alternative to conventional surgical resection for inoperable glioblastoma. This protocol describes an optimized pre-clinical mouse model that can be used to study treatment effects or adjuvant and combinatorial treatments.
