Establishing a Swine Model to Study Uterus Dynamic Preservation and TransplantationLucile Cabanel 1,2,3, Haïzam Oubari 1,2,3, Ludivine Dion 4, Vincent Lavoué 4, Mark A. Randolph 2,3, Curtis L. Cetrulo 2,3,5, Korkut Uygun 1,2, Alexandre G. Lellouch 1,2,3,5, Yanis Berkane 1,2,6,7, Basak E. Uygun 1,2
1Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, 2Shriners Children's Boston, 3Plastic Surgery Research Laboratory, Department of plastic and reconstructive surgery, Massachusetts General Hospital, Harvard Medical School, 4Department of Gynecology and Obstetrics, CHU de Rennes, University of Rennes, 5Division of Plastic Surgery Research, Vascularized Composite Allotransplantation Program Development, Cedars-Sinai Hospital, 6Department of Plastic, Reconstructive and Aesthetic Surgery, CHU de Rennes, University of Rennes, 7SITI Laboratory, UMR1236 INSERM, Établissement Français du Sang, University of Rennes
A detailed and reproducible swine uterus model is described, from surgical procurement to the initiation of machine perfusion, allowing for the study of uterus preservation in transplantation.