A Comprehensive Pipeline to Assess the Efficiency of Human Erythropoiesis In Vitro and Ex VivoCéline Philippe 1, Shoshana Burke 2, Kevin Rouault-Pierre 2
1Centre de Lutte contre le cancer Eugène Marquis, INSERM U1242, University of Rennes, 2Barts Cancer Institute, Queen Mary University of London
Modeling erythropoiesis provides a valuable chance to comprehend the biological significance of actors in this process and to evaluate novel therapeutic approaches that may alleviate differentiation defects. Here, we describe a simple and reliable method to efficiently differentiate CD34+ hematopoietic stem and progenitor cells ex vivo.
