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University of Aachen Medical Center

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Pseudofracture: An Acute Peripheral Tissue Trauma Model
Sophie S. Darwiche 1, Philipp Kobbe 2, Roman Pfeifer 2, Lauryn Kohut 1, Hans-Christoph Pape 2, Timothy Billiar 1
1Department of Surgery, University of Pittsburgh, 2Department of Orthopedic Surgery, University of Aachen Medical Center

Pseudofracture, a reproducible murine model of sterile musculoskeletal trauma, allows for evaluation of late term post-traumatic immune responses. This article describes the procedural execution of the model step by step, including the potential for experimental model combinations to permit study of multiple trauma.

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