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University of Texas

3 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Examining Local Network Processing using Multi-contact Laminar Electrode Recording
Bryan J. Hansen 1, Sarah Eagleman 1, Valentin Dragoi 2
1Graduate School of Biomedical Science, Neuroscience Program, University of Texas , 2Department of Neurobiology and Anatomy, University of Texas

A fundamental issue in our understanding of cortical circuitry is how networks in different cortical layers encode sensory information. Here we describe electrophysiological techniques utilizing multi-contact laminar electrodes to record single-units and local field potentials and present analyses to identify cortical layers.

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Medicine

A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice
Jacqueline F. Donoghue 1, Oliver Bogler 2, Terrance G. Johns 1
1Monash Institute of Medical Research , 2MD Anderson Cancer Centre, University of Texas

In order to evaluate novel therapeutic paradigms for the treatment of glioma, physiological relevant models are essential. We utilize an implantable guide screw procedure for establishment of intracranial xenograft models that is more rapid and safer than stereotactic approaches.

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Medicine

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
Laurence E. Court 1, Kelly Kisling 1, Rachel McCarroll 1, Lifei Zhang 1, Jinzhong Yang 1, Hannah Simonds 2, Monique du Toit 2, Chris Trauernicht 2, Hester Burger 3, Jeannette Parkes 3, Mike Mejia 4, Maureen Bojador 4, Peter Balter 1, Daniela Branco 1, Angela Steinmann 1, Garrett Baltz 1, Skylar Gay 1, Brian Anderson 1, Carlos Cardenas 1, Anuja Jhingran 5, Simona Shaitelman 5, Oliver Bogler 6, Kathleen Schmeller 7, David Followill 1, Rebecca Howell 1, Christopher Nelson 1, Christine Peterson 8, Beth Beadle 5,9
1Department of Radiation Physics, University of Texas MD Anderson Cancer Center, 2Department of Radiation Oncology, Stellenbosch University and Tygerberg Hospital, 3Departments of Radiation Oncology and Medical Physics, Groote Schuur Hospital and University of Cape Town, 4Department of Radiation Oncology, University of Santo Tomas Hospital, Benavides Cancer Institute, 5Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, 6Academic Affairs, University of Texas MD Anderson Cancer Center, 7Department of Gynecological Oncology and Reproductive Medicine, University of Texas MD Anderson Cancer Center, 8Department of Biostatistics, University of Texas MD Anderson Cancer Center, 9Department of Radiation Oncology, Stanford University

Radiation therapy is a highly complex cancer treatment that requires multiple specialists to create a treatment plan and provide quality assurance (QA) prior to delivery to a patient. This protocol describes the use of a fully automated system, the Radiation Planning Assistant (RPA), to create high-quality radiation treatment plans.

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