Warsaw University of Technology

3 ARTICLES PUBLISHED IN JoVE

Chemistry

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Olga Karagiaridi¹, Wojciech Bury^1,2, Amy A. Sarjeant¹, Joseph T. Hupp¹, Omar K. Farha^1,3

¹Department of Chemistry, Northwestern University, ²Department of Chemistry, Warsaw University of Technology, ³Department of Chemistry, Faculty of Science, King Abdulaziz University

Synthesis, activation, and characterization of intentionally designed metal-organic framework materials is challenging, especially when building blocks are incompatible or unwanted polymorphs are thermodynamically favored over desired forms. We describe how applications of solvent-assisted linker exchange, powder X-ray diffraction in capillaries and activation via supercritical CO₂ drying, can address some of these challenges.

Bioengineering

Building Up Skin Models for Numerous Applications - from Two-Dimensional (2D) Monoculture to Three-Dimensional (3D) Multiculture

Adrianna Maria Piasek^*1, Iryna Levkovych^*1, Paulina Musolf¹, Hanna Chmielewska¹, Aneta Ścieżyńska², Anna Sobiepanek¹

¹Chair of Drug and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, ²Department of Histology and Embryology, Medical University of Warsaw

Here, we present inexpensive and simple procedures to introduce various 3D skin models for routine research in a cell culture laboratory. Researchers can create models tailored to their needs without relying on commercially available models.

Neuroscience

Motion-Acuity Test for Visual Field Acuity Measurement with Motion-Defined Shapes

Marco Ninghetto¹, Michał Wieteska^2,3, Anna Kozak¹, Kamil Szulborski⁴, Tomasz Gałecki⁴, Jacek Szaflik⁴, Kalina Burnat¹

¹Nencki Institute of Experimental Biology, Polish Academy of Sciences, ²Mossakowski Medical Research Institute, Polish Academy of Sciences, ³Institute of Radio Electronics and Multimedia Technology, Warsaw University of Technology, ⁴Department of Ophthalmology, Medical University of Warsaw

A novel motion-based acuity test that allows the assessment of central and peripheral visual processing in low-vision and healthy individuals, along with goggles limiting peripheral vision compatible with MRI protocols, are described here. This method offers a comprehensive vision assessment for functional impairments and dysfunctions of the visual system.