Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain EdemaEmil Zeynalov 1, Susan M. Jones 1, J. Paul Elliott 2
1Neurotrauma Research, Swedish Medical Center, 2Neurosurgery, Colorado Brain and Spine Institute
Our studies have revealed that the beneficial effects of conivaptan are dependent on the method of delivery after experimental stroke in mice. We have developed a research protocol for delivery of the receptor blocker via IV catheter on stroke-evoked brain edema formation in mice.
