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Monash Institute of Medical Research

1 ARTICLES PUBLISHED IN JoVE

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Medicine

A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice
Jacqueline F. Donoghue 1, Oliver Bogler 2, Terrance G. Johns 1
1Monash Institute of Medical Research , 2MD Anderson Cancer Centre, University of Texas

In order to evaluate novel therapeutic paradigms for the treatment of glioma, physiological relevant models are essential. We utilize an implantable guide screw procedure for establishment of intracranial xenograft models that is more rapid and safer than stereotactic approaches.

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