Engineering of Human Blood-Induced Microglia-like Cells for Reverse-Translational Brain ResearchSota Kyuragi *1, Shogo Inamine *1, Masahiro Ohgidani 1,2, Takahiro A. Kato 1
1Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 2Department of Functional Anatomy and Neuroscience, Asahikawa Medical University
This study delineates a novel approach for the establishment of human monocyte-derived microglia-like (iMG) cells that enable the indirect assessment of brain inflammation. This presents a cellular model that may be beneficial to research focusing on potential inflammation of the brain and associated neuropsychiatric disorders.