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Faculdade de Farmácia da Universidade de Lisboa

1 ARTICLES PUBLISHED IN JoVE

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Chemistry

Lethality Bioassay Using Artemia salina L.
Márcia Santos Filipe *1,2, Vera M. S. Isca *1,3, Epole Ntungwe N. 1,2, Salvatore Princiotto 1, Ana Maria Díaz-Lanza 2, Patrícia Rijo 1,3
1CBIOS - Lusófona University's Center for Research in Biosciences & Health Technologies, Universidade Lusófona de Humanidades e Tecnologias, 2Facultad de Farmacia, Departamento de Ciencias Biomédicas (Área de Farmacologia; Nuevos agentes antitumorales, Acción tóxica sobre células leucémicas), Universidad de Alcalá de Henares, 3Instituto de Investigação do Medicamento (iMed.ULisboa), Faculdade de Farmácia da Universidade de Lisboa

This work aims to evaluate and review the Artemia salina lethality bioassay procedure, also identified as brine shrimp lethality assay. This simple and cheap method gives information about the general toxicity (considered as a preliminary toxicity evaluation) of samples, namely, natural products.

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