cobas Screening and Improved Cervical Cancer Screening and PreventionJane S. Gibson 1, Ricki Pollycove 2, Thomas C. Wright 3
1Department of Clinical Sciences College of Medicine, University of Central Florida, 2Division of Gynecology, California Pacific Medical Center, 3Department of Pathology and Cell Biology, Columbia University
In order to reduce cervical cancer incidence we need to increase the sensitivity of methods used for screening. Testing for "high-risk" types of HPV greatly improves sensitivity compared to cervical cytology, but is generally thought to reduce specificity. Incorporating genotyping for HPV 16 and 18 together with "high-risk" HPV testing reduces the impact of lower specificity.
