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MCL Laboratories Inc.

1 ARTICLES PUBLISHED IN JoVE

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Immunology and Infection

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
Thomas Bodmer 1, Angelika Ströhle 2
1Institute for Infectious Diseases, University of Bern, 2MCL Laboratories Inc.

The Xpert MTB/RIF test integrates sample decontamination, hands-free operation, on-board sample processing, and ultra-sensitive hemi-nested PCR for the simultaneous detection of Mycobacterium tuberculosis and rifampicin resistance, either in expectorated sputum or concentrated sputum sediments, in approximately two hours. Testing is standardized and requires only moderate laboratory infrastructure and training.

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