Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow CellsCarolyn G. Conant 1, Michael A. Schwartz 1, Tanner Nevill 1, Cristian Ionescu-Zanetti 1
1Fluxion Biosciences, Inc.
The platelet adhesion cascade takes place in the presence of shear flow, a factor not accounted for in conventional (static) well-plate assays. This article reports on a platelet-aggregation assay utilizing a microfluidic well-plate format to emulate physiological shear flow conditions.