University of North Carolina and North Carolina State University

1 ARTICLES PUBLISHED IN JoVE

Bioengineering

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Philip R. Miller^1,2, Shelby A. Skoog¹, Thayne L. Edwards², David R. Wheeler², Xiaoyin Xiao², Susan M. Brozik², Ronen Polsky², Roger J. Narayan¹

¹Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, ²Department of Biosensors and Nanomaterials, Sandia National Laboratories

This article details the construction of a multiplexed microneedle-based sensor. The device is being developed for in situ sampling and electrochemical analysis of multiple analytes in a rapid and selective manner. We envision clinical medicine and biomedical research uses for these microneedle-based sensors.