DFG - Research Center and Cluster of Excellence for Regenerative Therapies Dresden, Germany

1 ARTICLES PUBLISHED IN JoVE

Neuroscience

Expansion of Embryonic and Adult Neural Stem Cells by In Utero Electroporation or Viral Stereotaxic Injection

Benedetta Artegiani^*1, Christian Lange^*1, Federico Calegari¹

¹DFG - Research Center and Cluster of Excellence for Regenerative Therapies Dresden, Germany

Controlling the expansion of somatic stem cells is a major factor hampering their study and use in therapy. Here we describe a system to temporally control neural stem cells expansion during development and adulthood, which can be used to increase the number of neurons generated in the mouse brain.