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Shandong University of Traditional Chinese Medicine

8 ARTICLES PUBLISHED IN JoVE

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JoVE Journal

Creating Virtual-hand and Virtual-face Illusions to Investigate Self-representation
Ke Ma 1, Dominique P. Lippelt 1, Bernhard Hommel 1
1Cognitive Psychology Unit, Leiden University

Here, we describe virtual-hand and virtual-face illusion paradigms that can be used to study body-related self-perception/-representation. They have already been used in various studies to demonstrate that, under specific conditions, a virtual hand or face can be incorporated into one's body representation, suggesting that body representations are rather flexible.

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Biochemistry

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Bing Sun 1, Yue-zhang Yin 2, Jing Xiao 1
1Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences & Peking Union Medical College, 2Shandong University of Traditional Chinese Medicine

Clinically, estrogen deficiency in menopausal women may aggravate the incidence of lipid disruption and atherosclerosis. We established an in vivo estrogen deficiency model by bilateral ovariectomy via a double dorsal-lateral incision in apoE-/- mice. The mouse model is applicable for screening exogenous estrogen treatments of cardiovascular dysfunction after menopause.

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Medicine

A New Model of Heart Failure Post-Myocardial Infarction in the Rat
Honglei Li 1,2, Jiansheng Huang 3, Caihong Liu 1, Zhentao Zhang 3, Kuiquan Song 2, Ke Ma 1, Connor W. Dennewitz 3, Shijun Wang 1,4
1College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, 2Department of Intensive Care Unit, Jinan Municipal Hospital of Traditional Chinese Medicine, 3Department of Medicine, Vanderbilt University Medical Center, 4Shandong Co-Innovation Center of Classic TCM Formula, Shandong Provincial Education Department

We successfully developed a reliable and reproducible model of heart failure post-myocardial infarction in the rat without ventilation or exteriorization of the heart. This simplifies the procedure and benefits the further studies about the potential mechanisms behind the heart failure.

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Biology

Surgically Induced Cardiac Volume Overload by Aortic Regurgitation in Mouse
Jian Wu *1, Shijun Wang *1, Le Kang *1, Chunjie Yang *1, Jianguo Jia 1, Xingxu Wang 2, Ge Wei 1, Xuan Li 1, Jieyun You 2, Yunzeng Zou 1
1Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, 2Department of Cardiovascular Medicine, Shanghai East Hospital, School of Medicine, Tongji University

This protocol presents a practical guide on the surgery for creation of aortic regurgitation (AR) in the mouse. Assessment of the AR mouse by echocardiography and invasive hemodynamic measurement recapitulates its clinically relevant characteristics of volume overload-induced eccentric hypertrophy, suggesting its promising application in the study of cardiac hypertrophy.

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Medicine

Tuina in a Frozen Shoulder Rat Model: An Efficient and Reproducible Protocol
Yingjie Qiao 1, Yanhong Yang 2, Jianmin Wang 3, Muzhen Li 1, Lijun Zheng 1, Huadong Li 3, Shidong Zhang 1
1College of Acupuncture and Tuina, Shandong University of Traditional Chinese Medicine, 2Department of Tuina, Jinan Massage Hospital, 3Department of Tuina, Shandong University of Traditional Chinese Medicine Affiliated Hospital

This study develops an efficient and reproducible Tuina protocol for treating frozen shoulder established in a rat model. This approach will help to study the Tuina therapy treatment method for frozen shoulders.

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Immunology and Infection

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis
Wen-Yan Yu 1, Xu-Hao Li 1, Zhi-Xia Jia 2, Yi Hou 1, Tian-tian Dong 3, Xing-Xin Wang 1, Yuan-Xiang Liu 2, Ji-Guo Yang 1
1School of Acupuncture-Moxibustion and Tuina, Shandong University of Traditional Chinese Medicine, 2School of First Clinical Medicine, Shandong University of Traditional Chinese Medicine, 3External Treatment Center, Affiliated Hospital of Shandong University of Traditional Chinese Medicine

This paper describes in detail the operation procedures and precautions to be taken during Du-moxibustion in the treatment of ankylosing spondylitis in experimental mice.

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Medicine

Tuina Intervention in Rabbit Model of Knee Osteoarthritis
Shidong Zhang *1, Xuan Zhang *2, Gangyi Sun 3, Kai Wang 1, Yingjie Qiao 1, Yanling He 3, Muzhen Li 1, Huadong Li 3, Lijun Zheng 3
1Shandong University of Traditional Chinese Medicine, 2Liaoning University of Traditional Chinese Medicine, 3Shandong University of Traditional Chinese Medicine Affiliated Hospital

The protocol describes a method for Tuina intervention in a rabbit model of knee osteoarthritis.

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Medicine

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
Xiaofan Wang 1, Li Li 1, Qingbao Wang 1, Hongsheng Bi 2, Hua Fan 2, Xingrong Wang 2, Peng Ji 2
1Shandong University of Traditional Chinese Medicine, 2Shandong Clinical Medicine Research Center, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine

This article provides a step-by-step guide to correcting presbyopia with a monocular bi-aspheric ablation profile.

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