Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti Sara Dörken 1, Kira Duhm 1, Birte Viebrock 1, Lara Linnemann 1, Lennart Heepmann 1, Wiebke Hartmann 1, Jennifer Antwi-Ekwuruke 1, M. Saleh Yunus 1,2, Minka Breloer 1,3
1Section Interface, Helminth Immunology Group, Bernhard Nocht Institute for Tropical Medicine, 2Institute for Infection Research and Vaccine Development, University Hospital Eppendorf, 3Department for Biology, University Hamburg
Strongyloides ratti is a parasitic nematode that causes transient infections in laboratory mice, displaying tissue-migrating and intestinal life stages. Here, we present a protocol for the maintenance of the parasite cycle in rats and experimental infection of mice, including parasite quantification in the head, lung, and intestine.
