Modified Technique for Coronary Artery Ligation in MiceYangzhen Shao 1, Björn Redfors 1, Elmir Omerovic 1
1Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg
The surgical procedure used to induce experimental myocardial infarction in mice begins with left thoracotomy between the third and the fourth ribs in order to visualize the anterior surface of the heart and left lung. The left coronary artery is ligated, the chest is closed and the mouse is allowed to recover spontaneously.
