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Malawi-Liverpool-Wellcome Trust Clinical Research Programme

1 ARTICLES PUBLISHED IN JoVE

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Immunology and Infection

A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting
Dumizulu L. Tembo 1, Jacqui Montgomery 1, Alister G. Craig 2, Samuel C. Wassmer 3
1Malawi-Liverpool-Wellcome Trust Clinical Research Programme, 2Liverpool School of Tropical Medicine, 3Department of Microbiology, Division of Medical Parasitology, New York University School of Medicine

This method investigates the platelet-mediated clumping phenotype of Plasmodium falciparum-infected erythrocytes (pRBC) in clinical isolates. This is performed by isolating and co-incubating platelet-rich plasma and a suspension of pRBC.

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