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Jiangsu university

2 ARTICLES PUBLISHED IN JoVE

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Bioengineering

Bioinspired Soft Robot with Incorporated Microelectrodes
Ting Wang 1,2, Bianca Migliori 1,3, Beatrice Miccoli 1,4, Su Ryon Shin 1
1Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 2School of Medicine, Jiangsu University, 3Tech4Health and Neuroscience Institutes, NYU Langone Health, 4Department of Electronics and Telecommunication, Politecnico di Torino

A bioinspired scaffold is fabricated by a soft photolithography technique using mechanically robust and electrically conductive hydrogels. The micropatterned hydrogels provide directional cardiomyocyte cell alignment, resulting in a tailored direction of actuation. Flexible microelectrodes are also integrated into the scaffold to bring electrical controllability for a self-actuating cardiac tissue.

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JoVE Core

Direct Reprogramming of Mouse Fibroblasts into Melanocytes
Yi-Xuan Zhang 1,2, Li-Ping Liu 1,2, Ming Jin 1,2, Hui Sun 1,2, Han-Lin Zhang 1,2, Yu-Mei Li 1,2
1Institute for Regenerative Medicine, Jiangsu University, 2Department of Dermatology, Affiliated Hospital of Jiangsu University

Here, we describe an optimized direct reprogramming system for melanocytes and a high-efficiency, concentrated virus packaging system that ensures smooth direct reprogramming.

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