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2 ARTICLES PUBLISHED IN JoVE

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JoVE Journal

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry
Ludovico Carbone 1, Paul Fulda 1, Charlotte Bond 1, Frank Brueckner 1, Daniel Brown 1, Mengyao Wang 1, Deepali Lodhia 1, Rebecca Palmer 1, Andreas Freise 1
1School of Physics and Astronomy, University of Birmingham

Large laser-interferometers are being constructed to create a new type of astronomy based on gravitational waves. Their sensitivities, as for many other high-precision experiments, are approaching fundamental noise limits such as the atomic vibration of their components. We are pioneering technologies to overcome these limits using novel laser beam shapes.

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Biology

Reduced-gravity Environment Hardware Demonstrations of a Prototype Miniaturized Flow Cytometer and Companion Microfluidic Mixing Technology
William S. Phipps *1, Zhizhong Yin *1, Candice Bae 1, Julia Z. Sharpe 1, Andrew M. Bishara 2, Emily S. Nelson 3, Aaron S. Weaver 3, Daniel Brown 4, Terri L. McKay 3, DeVon Griffin 3, Eugene Y. Chan 1
1DNA Medicine Institute, 2Harvard Medical School, 3NASA Glenn Research Center, 4ZIN Technologies

Spaceflight blood diagnostics need innovation. Few demonstrations have been published illustrating in-flight, reduced-gravity health diagnostic technology. Here we present a method for construction and operation of a parabolic flight test rig for a prototype point-of-care flow-cytometry design, with components and preparation strategies adaptable to other setups.

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