Kangwon National University

4 ARTICLES PUBLISHED IN JoVE

Cancer Research

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles

Ji-Eun Chang¹, Hyun-Jong Cho², Sanghoon Jheon^1,3

¹Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, ²College of Pharmacy, Kangwon National University, ³Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine

Photodynamic therapy (PDT) is an alternative choice for lung cancer treatment. To increase the therapeutic effect of PDT, lung cancer-targeted nanoparticles combined with chemotherapy were developed. Both in vitro and in vivo anticancer efficacies of PDT with prepared nanoparticles were evaluated.

Environment

Cortisol Extraction from Sturgeon Fin and Jawbone Matrices

Jalil Ghassemi Nejad^1,2, Mohammad Ataallahi¹, Mohammad H. Salmanzadeh³, Kyung T. Park³, Hong G. Lee^2,4, Alireza Shoae⁵, Atieh Rahimi⁶, Kyung I. Sung¹, Kyu H. Park¹

¹College of Animal Life Sciences, Kangwon National University, ²Team of An Educational Program for Specialists in Global Animal Science, Brain Korea 21 Plus Project, Konkuk University, ³Persian Gesture, ⁴Department of Animal Science and Technology, College of Animal Bioscience and Technology, Konkuk University, ⁵Department of Animal Science, Animal Physiology, AgResearch, ⁶Faculty of Agriculture, Animal Science Department, Ferdowsi University of Mashhad

In this study, we present a protocol for cortisol extraction from the fin and jawbone of sturgeon species. Fin and jawbone cortisol levels were further examined by comparing two washing solvents followed by ELISA assays. This study piloted the feasibility of jawbone cortisol as a novel stress indicator.

Engineering

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Doohyeon Kim¹, Hyung Kyu Huh², Hojin Ha¹

¹Interdisciplinary Program in Biohealth-Machinery Convergence Engineering, Kangwon National University, ²Medical Device Development Center, DGMIF

Aortic regurgitation is an aortic valve heart disease. This manuscript demonstrates how four-dimensional flow magnetic resonance imaging can evaluate aortic regurgitation using in vitro heart valves mimicking aortic regurgitation.

Engineering

Particle Image Velocimetry Investigation of Hemodynamics via Aortic Phantom

Jihun Kang¹, Hojin Ha¹

¹Interdisciplinary Program in Biohealth-Machinery Convergence Engineering, Kangwon National University

The present protocol describes particle image velocimetry (PIV) measurements performed to investigate the sinus flow through the in vitro setup of the transcatheter aortic valve (TAV). The hemodynamic parameters based on velocity are also determined.