Indian Institute of Technology Gandhinagar

3 ARTICLES PUBLISHED IN JoVE

Neuroscience

A Human-machine-interface Integrating Low-cost Sensors with a Neuromuscular Electrical Stimulation System for Post-stroke Balance Rehabilitation

Deepesh Kumar¹, Abhijit Das², Uttama Lahiri¹, Anirban Dutta^3,4

¹Indian Institute of Technology Gandhinagar, ²AMRI Institute of Neurosciences, ³Institut national de recherche en informatique et en automatique (INRIA), ⁴Leibniz Research Centre for Working Environment and Human Factors (IfADo)

A novel low-cost human-machine interface for interactive post-stroke balance rehabilitation system is presented in this article. The system integrates off-the-shelf low-cost sensors towards volitionally driven electrotherapy paradigm. The proof-of-concept software interface is demonstrated on healthy volunteers.

Chemistry

Developing Photosensitizer-Cobaloxime Hybrids for Solar-Driven H₂ Production in Aqueous Aerobic Conditions

Ab Qayoom Mir¹, Dependu Dolui¹, Shikha Khandelwal¹, Harshil Bhatt², Beena Kumari¹, Sanmitra Barman³, Sriram Kanvah¹, Arnab Dutta¹

¹Chemistry Discipline, Indian Institute of Technology Gandhinagar, ²Chemistry Department, Uka Tarsadia University, ³Applied Sciences Department, BML Munjal University

We have directly incorporated a stilbene-based organic dye into a cobaloxime core to generate a photosensitizer-catalyst dyad for photocatalytic H₂ production. We have also developed a simple experimental setup for evaluating the light-driven H₂ production by photocatalytic assemblies.

Biochemistry

Single-Molecule Analysis of Sf9 Purified Superprocessive Kinesin-3 Family Motors

Pushpanjali Soppina^1,2, Dipeshwari J. Shewale¹, Pradeep K. Naik², Virupakshi Soppina¹

¹Discipline of Biological Engineering, Indian Institute of Technology Gandhinagar, ²Department of Biotechnology and Bioinformatics, Sambalpur University

This study details purification of KIF1A(1-393LZ), a member of kinesin-3 family, using Sf9-baculovirus expression system. In vitro single-molecule and multi-motor gliding analysis of these purified motors exhibited robust motility properties comparable to motors from mammalian cell lysate. Thus, Sf9-baculovirus system is amenable to express and purify motor protein of interest.