Università Cattolica del Sacro Cuore

2 ARTICLES PUBLISHED IN JoVE

Biology

The use of Biofeedback in Clinical Virtual Reality: The INTREPID Project

Claudia Repetto¹, Alessandra Gorini¹, Cinzia Vigna¹, Davide Algeri¹, Federica Pallavicini¹, Giuseppe Riva^1,2

¹Applied Technology for Neuro-Psychology Lab, Istituto Auxologico Italiano, ²Psychology Department, Università Cattolica del Sacro Cuore

The Project on Virtual Reality Intelligent Multi-sensor System for the Treatment of Anxiety-related Disorders (INTREPID) is aimed at developing a multi-sensor context-aware virtual reality system for the treatment of anxiety-related disorders.

Immunology and Infection

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Adele De Ninno¹, Francesca Romana Bertani¹, Annamaria Gerardino¹, Giovanna Schiavoni², Martina Musella³, Claudia Galassi³, Fabrizio Mattei², Antonella Sistigu^3,4, Luca Businaro¹

¹CNR Institute for Photonics and Nanotechnology, ²Dept. of Oncology and Molecular Medicine, Istituto Superiore di Sanità, ³Istituto di Patologia Generale, Università Cattolica del Sacro Cuore, ⁴Tumor Immunology and Immunotherapy Unit, IRCCS Regina Elena National Cancer Institute

In the age of immunotherapy and single-cell genomic profiling, cancer biology requires novel in vitro and computational tools for investigating the tumor-immune interface in a proper spatiotemporal context. We describe protocols to exploit tumor-immune microfluidic co-cultures in 2D and 3D settings, compatible with dynamic, multiparametric monitoring of cellular functions.