the second affiliated hospital of nanchang university

3 ARTICLES PUBLISHED IN JoVE

Medicine

Application of Straight-needle, Three-tailed, Knot-free, Peritoneal Sutures in Laparoscopic Transabdominal Preperitoneal Hernia Repair

Ning Ma^*1, Zhen Zong^*2, Fu-xing Tang¹, En-min Huang¹, Tao Ma¹, Wei-sheng Yang¹, Jia-lin Chen¹, Shuang Chen¹, Tai-cheng Zhou¹

¹Department of Gastroenterological Surgery and Hernia Center, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, ²Department of Gastrointestinal Surgery, the Second Affiliated Hospital of Nanchang University

Here, we present a protocol to introduce a new peritoneal suture method. This method is called straight-needle, three-tailed, knot-free suture, and we will outline the manufacturing method and clinical application of this suture in detail.

Medicine

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma

Qiang Li^*1, Xiaolan Wang^*1,2, Deju Li^*1, Yulong Liu^*3, Kangshou Liu¹, Junjie Liang¹, Jian Sun¹, Quan Jiang¹, Jiexing Li¹, Zhilong Liu¹, Jian Gong⁴, Leyang Xiang¹, Zhidong Jia¹, Zhiwei Chen¹, Mingrong Cao¹, Yuchuan Jiang^1,5

¹Department of Hepatobiliary Surgery, The First Affiliated Hospital, Jinan University, ²Dongpu Branch, The First Affiliated Hospital, Jinan University, ³Department of Vascular Intervention, The First Affiliated Hospital, Jinan University, ⁴Department of Nuclear Medicine, The First Affiliated Hospital, Jinan University, ⁵Department of Gastroenterology, The Second Affiliated Hospital of Nanchang University

This study illustrates the methodological potential of combining Yttrium-90 Trans-Arterial Radioembolization (Y-90 TARE) with an anti-PD-1 monoclonal antibody as an effective neoadjuvant strategy leading to hepatectomy in hepatocellular carcinoma (HCC) patients with a high initial recurrence risk. It emphasizes the safety, feasibility, and step-by-step procedural guidance of this approach.

Medicine

Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

Jianwei Yi¹, Zhigang Hu^1,2, Hengchang Zhu¹, Yumin Qiu¹, Binghai Zhou¹, Kai Wang^1,2

¹Hepato-Biliary-Pancreatic Surgery Division, Department of General Surgery, The Second Affiliated Hospital of Nanchang University, ²Jiangxi Province Engineering Research Center of Hepatobiliary Disease

Perihilar cholangiocarcinoma (pCCA) is a highly malignant and aggressive tumor, with radical resection being the only curative treatment available. With continuous advancements in laparoscopic techniques and instruments, laparoscopic radical surgery for pCCA is now considered technically safe and feasible. However, due to the high complexity of the surgery and the lack of evidence-based clinical support, laparoscopic radical surgery for type IIIb pCCA is performed only in a few large hepatobiliary centers. Current guidelines recommend left hemihepatectomy combined with total caudate lobectomy and standardized lymphadenectomy for resectable type IIIb pCCA. Therefore, in this article, we provide a detailed description of the surgical steps and technical points of complete laparoscopic left hemihepatectomy combined with total caudate lobectomy, regional lymphadenectomy, and right hepatic duct-jejunal Roux-en-Y anastomosis in patients with type IIIb pCCA, using fluorescence navigation technology to enhance surgical precision and safety. By adhering to standardized surgical procedures and precise intraoperative techniques, we offer an effective means to improve patient outcomes.