The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug EfficacyJennifer Chua 1, Nathan A. Fisher 2, Shane D. Falcinelli 1, David DeShazer 1, Arthur M. Friedlander 3
1Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, 2Southern Research, 3Headquarters Division, United States Army Medical Research Institute of Infectious Diseases
We present a protocol to utilize the Madagascar hissing cockroach as an alternative non-mammalian animal model to conduct bacterial virulence, pathogenesis, drug toxicity, drug efficacy, and innate immune response studies.
