Kaplan Medical Center

3 ARTICLES PUBLISHED IN JoVE

Bioengineering

Dana Egozi^*1, Yulia Shandalov^*2, Alina Freiman^2,3, Dekel Rosenfeld², David Ben-Shimol⁴, Shulamit Levenberg²

¹Department of Plastic Surgery, Kaplan Medical Center, ²Biomedical Engineering, Technion Israel Institute of Technology, ³Interdepartmental Program in Biotechnology, Technion Israel Institute of Technology, ⁴Medicine Department, Technion Israel Institute of Technology

To date, thick tissue defects are typically reconstructed by applying autologous tissue flaps or engineered tissues. In this protocol, we present a new method for engineering vascularized tissue flap bearing an autologous pedicle, to serve as a substitute to autologous flaps.

Cancer Research

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Dimitri Gaber¹, Michal Aharoni-Simon¹, Ortal Zaks¹, Keren Ben-Yaakov¹, Ziv Rotfogel^1,2, Hana Leiba^1,2, Avital Eisenberg-Lerner^*1, Arie L. Marcovich^*1,2

¹Ophthalmology Research Laboratory, Kaplan Medical Center, ²Department of Ophthalmology, Kaplan Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem

The present protocol describes the implantation and evaluation of melanoma in the murine choroid utilizing optical coherence tomography.

Biology

Intracameral Injection in Rats with Low Risk of Adverse Effects

Oriel Ratzon^*1, Mor Schlesinger^*1, Keren Ben-Yaakov¹, Ortal Zaks¹, Ziv Rotfogel^1,2, Arie L. Marcovich^1,2, Avital Eisenberg-Lerner¹

¹Ophthalmology Research Laboratory, Kaplan Medical Center, ²Department of Ophthalmology, Kaplan Medical Center, Faculty of Medicine, Hebrew University of Jerusalem

This protocol describes a technique for intracameral injection in rats using a central corneal incision and a long tunnel into the anterior chamber. This injection method minimizes the risk of inducing inadvertent tissue damage and thereby improves precision and reproducibility.