Measurement of Mitochondrial Membrane Potential In Vivo using a Genetically Encoded Voltage IndicatorRun-Zhou Yang 1, Dian-Dian Wang 2,3, Sen-Miao Li 2,3, Pei-Pei Liu 1, Jian-Sheng Kang 1,2,3
1Clinical Systems Biology Laboratories, The First Affiliated Hospital of Zhengzhou University, 2Department of Neurology, The First Affiliated Hospital of Zhengzhou University, 3The Academy of Medical Sciences, Zhengzhou University
This protocol describes the application of mitochondria-targeted genetically encoded voltage indicators (GEVIs). These GEVIs offer a significant advantage over traditional mitochondrial membrane potential dyes by enabling specific, in vivo, and real-time monitoring of mitochondrial membrane potential.
