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The First Affiliated Hospital of Nanjing Medical University

1 ARTICLES PUBLISHED IN JoVE

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Biology

Assessing Insulin Clearance in Mice via In Situ Liver Perfusion
Zhenzhen Fu *1, Yishu Wang *1, Lijuan Chen 1, Zhengping Hou 1, Yingyun Gong 1, Hongwen Zhou 1
1Department of Endocrinology and Metabolism, the First Affiliated Hospital of Nanjing Medical University

Hepatic insulin clearance is critical for regulating glucose homeostasis. This article describes a user-friendly hepatic perfusion procedure for directly evaluating the hepatic insulin clearance rate in situ in mice.

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