Single-Particle Interferometric Reflectance Imaging Characterization of Individual Extracellular Vesicles and Population DynamicsFengyan Deng 1, Anamika Ratri 1, Clayton Deighan 2, George Daaboul 2, Paige C. Geiger 1, Lane K. Christenson 1
1Department of Molecular and Integrative Physiology, University of Kansas Medical Center, 2NanoView Biosciences
This protocol presents single-particle interferometric reflectance imaging that is designed for the multi-level and comprehensive measurements of extracellular vesicles (EV) size, EV count, EV phenotype, and EV biomarker colocalization.