Performing In Vivo and Ex Vivo Electrical Impedance Myography in RodentsMarie Mortreux 1, Janice A. Nagy 1, Haowen Zhong 1, Dong-Min Sung 1, Holly A. Concepcion 1, Melanie Leitner 2, Laura Dalle Pazze 3, Seward B. Rutkove 1
1Department of Neurology, Harvard Medical School - Beth Israel Deaconess Medical Center, 2Accelerating NeuroVentures, 3Charley's Fund
This article details how to perform in vivo (using surface and needle electrode arrays) and ex vivo (using a dielectric cell) electrical impedance myography on the rodent gastrocnemius muscle. It will demonstrate the technique in both mice and rats and detail the modifications available, (i.e., obese animals, pups).
