GABA-activated Single-channel and Tonic Currents in Rat Brain SlicesZhe Jin 1, Yang Jin 1, Bryndis Birnir 1
1Department of Neuroscience, Uppsala University, Sweden
We use the patch-clamp technique to measure GABA-activated single-channel currents (GABAA channels, GABAA receptors) and the synaptic and tonic currents they generate in neurons. Activation of the channels decreases neuronal excitability in health and disease 1,2,3,4.