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Uppsala University, Sweden

1 ARTICLES PUBLISHED IN JoVE

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Neuroscience

GABA-activated Single-channel and Tonic Currents in Rat Brain Slices
Zhe Jin 1, Yang Jin 1, Bryndis Birnir 1
1Department of Neuroscience, Uppsala University, Sweden

We use the patch-clamp technique to measure GABA-activated single-channel currents (GABAA channels, GABAA receptors) and the synaptic and tonic currents they generate in neurons. Activation of the channels decreases neuronal excitability in health and disease 1,2,3,4.

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