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4 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
Ifat Levy 1,2, Lior Rosenberg Belmaker 1, Kirk Manson 1, Agnieszka Tymula 3, Paul W. Glimcher 3,4,5
1Section of Comparative Medicine, Yale School of Medicine, 2Department of Neurobiology, Yale School of Medicine, 3Center for Neural Science, New York University , 4Department of Psychology, New York University , 5Department of Economics, New York University

Using functional MRI and behavioral methods to determine the neural representation of the subjective value of risky and ambiguous options in the human brain.

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Neuroscience

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
Daniela Schiller 1, Candace M. Raio 2, Elizabeth A. Phelps 3
1Departments of Psychiatry and Neuroscience, and Friedman Brain Institute, Mt. Sinai School of Medicine, 2Department of Psychology, New York University , 3Department of Psychology and Center for Neural Science, New York University

Conditioned fear can be diminished through an inhibitory process called extinction, but can resurface under conditions such as the passage of time or exposure to stress. Our protocol presents a novel way of preventing fear recovery by introducing extinction during the reconsolidation window (the re-storage phase of a reactivated memory).

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Neuroscience

Dissection and Immunohistochemistry of Larval, Pupal and Adult Drosophila Retinas
Hui-Yi Hsiao *1, Robert J. Johnston Jr. *1, David Jukam *1, Daniel Vasiliauskas *1, Claude Desplan 1, Jens Rister 1
1Department of Biology, New York University

The Drosophila retina is a crystal-like lattice composed of a small number of cell types that are generated in a stereotyped manner 1. Its amenability to sophisticated genetic analysis allows the study of complex developmental programs. This protocol describes dissections and immunohistochemistry of retinas at three discrete developmental stages, with a focus on photoreceptor differentiation.

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Biology

The Use of Chemostats in Microbial Systems Biology
Naomi Ziv 1, Nathan J. Brandt 1, David Gresham 1
1Center for Genomics and Systems Biology, Department of Biology, New York University

Cell growth rate is a regulated process and a primary determinant of cell physiology. Continuous culturing using chemostats enables extrinsic control of cell growth rate by nutrient limitation facilitating the study of molecular networks that control cell growth and how those networks evolve to optimize cell growth.

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