Methods for Intravenous Self Administration in a Mouse ModelElizabeth K. Kmiotek 1, Corey Baimel 1, Kathryn J. Gill 1
1Addictions Unit, McGill University Health Centre
The intravenous self-administration (IVSA) paradigm is considered to be the gold standard in examining the reinforcing properties of drugs of abuse in rodents. This manuscript outlines the experimental procedures and surgical techniques necessary to obtain reliable IVSA data. In particular, meticulous catheter implantation and maintenance are highlighted.
